Hypocapnic cerebral hypoperfusion: A biomarker of orthostatic intolerance
نویسندگان
چکیده
منابع مشابه
Hypocapnia and cerebral hypoperfusion in orthostatic intolerance.
BACKGROUND AND PURPOSE Orthostatic and other stresses trigger tachycardia associated with symptoms of tremulousness, shortness of breath, dizziness, blurred vision, and, often, syncope. It has been suggested that paradoxical cerebral vasoconstriction during head-up tilt might be present in patients with orthostatic intolerance. We chose to study middle cerebral artery (MCA) blood flow velocity ...
متن کاملOrthostatic Cerebral Hypoperfusion Syndrome
OBJECTIVE Orthostatic dizziness without orthostatic hypotension is common but underlying pathophysiology is poorly understood. This study describes orthostatic cerebral hypoperfusion syndrome (OCHOs). OCHOs is defined by (1) abnormal orthostatic drop of cerebral blood flow velocity (CBFv) during the tilt test and (2) absence of orthostatic hypotension, arrhythmia, vascular abnormalities, or oth...
متن کاملCerebral Perfusion in Subjects with Orthostatic Intolerance
INTRODUCTION Orthostatic intolerance is characterized by symptoms of lightheadedness, tiredness, palpitations, blurred vision and occasionally, by loss of consciousness during standing, which are relieved upon recumbency. These symptoms are suggestive of cerebral hypoperfusion, yet they occur in the absence of orthostatic hypotension. We therefore evaluated cerebral vasoregulation in patients w...
متن کاملCommon syndromes of orthostatic intolerance.
The autonomic nervous system, adequate blood volume, and intact skeletal and respiratory muscle pumps are essential components for rapid cardiovascular adjustments to upright posture (orthostasis). Patients lacking sufficient blood volume or having defective sympathetic adrenergic vasoconstriction develop orthostatic hypotension (OH), prohibiting effective upright activities. OH is one form of ...
متن کاملPediatric Disorders of Orthostatic Intolerance.
Orthostatic intolerance (OI), having difficulty tolerating an upright posture because of symptoms or signs that abate when returned to supine, is common in pediatrics. For example, ∼40% of people faint during their lives, half of whom faint during adolescence, and the peak age for first faint is 15 years. Because of this, we describe the most common forms of OI in pediatrics and distinguish bet...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0204419